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Hepatotoxicity :from genomics to in ...

Sahu, Saura C.

Hepatotoxicity :from genomics to in vitro and in vivo models /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Hepatotoxicity :/ editor, Saura C. Sahu.
其他題名:	from genomics to in vitro and in vivo models /
作者:	Sahu, Saura C.
出版者:	Chichester, West Sussex, England ;John Wiley & Sons, : c2007.,
面頁冊數:	xvi, 682 p. :ill. :
標題:	Drug-Induced Liver Injury - etiology -
ISBN:	9780470057162 (pbk. : alk. paper) : $cNT7500

Hepatotoxicity :from genomics to in vitro and in vivo models /
Sahu, Saura C.

Hepatotoxicity :from genomics to in vitro and in vivo models /editor, Saura C. Sahu. - Chichester, West Sussex, England ;John Wiley & Sons,c2007. - xvi, 682 p. :ill.

Includes bibliographical references and index.

ISBN: 9780470057162 (pbk. : alk. paper) : $cNT7500

LCCN: 2007038233Subjects--Topical Terms:

302783
Drug-Induced Liver Injury
--etiology

National Library of Medicine Call No.: 2008 B-170

Hepatotoxicity :from genomics to in vitro and in vivo models /
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245 0 0 $a Hepatotoxicity : $b from genomics to in vitro and in vivo models / $c editor, Saura C. Sahu.
260 # $a Chichester, West Sussex, England ; $a Hoboken, NJ, USA : $c c2007. $b John Wiley & Sons,
300 $a xvi, 682 p. : $b ill.
504 $a Includes bibliographical references and index.
595 0 $a Current in vitro models to study drug-induced liver injury / Julio C. Davila ... [et al.] -- Utilization of an in vitro hepatotoxicity test in the early stage of drug discovery / Ikuo Horii ... [et al.] -- Use of hepatocytes for characterizing a candidate drug's metabolism and drug interaction potential / Srikanth C. Nallani, John M. Strong and Shiew Mei Huang -- Human-based in vitro experimental systems for the evaluation of human drug safety / Albert P. Li -- Hepatocytes as a model for screening food-related hepatotoxins and studying mechanisms of their toxicity / Saura C. Sahu -- Some experimental models of liver damage / Pablo Muriel -- Application of short- and long-term hepatocyte cultures to predict toxicities / Gregor Tuschl ... [et al.] -- Biomarkers of mycotoxin exposure in liver toxicity / Angela J. Harris -- Mechanisms of toxic liver injury / Nora Anderson and J�urgen Borlak -- A role of cytochrome P450 in quinone-induced hepatotoxicity / Yasuhiro Ishihara and Norio Shimamoto -- A mechanistic view of troglitazone hepatotoxicity / Rawiwan Maniratanachote and Tsuyoshi Yokoi -- Role of the Kupffer cell in hepatotoxicity and hepatocarcinogenesis / James E. Klaunig ... [et al.] -- Sinusoidal cells in liver injury and repair / Carol C. Gardner and Debra L. Laskin -- Cytokines in liver diseases / Pablo Muriel -- Bile acids as modulators of apoptosis / Rui E. Castro ... [et al.] --
595 0 $a Drug-induced intrahepatic cholestasis by interaction with the hepatic bile salt export pump (BSEP) / Christoph Funk ... [et al.] -- Application of toxicogenomics in predicting hepatotoxicity- potentials and challenges / Wen Lin ... [et al.] -- Genomic profiling of liver injury / Kevin Gerrish and David E. Malarkey -- Use of DNA arrays in understanding hepatic test systems / Angela J. Harris and Daniel A. Casciano -- Prediction of hepatotoxicity based on the toxicogenomics database / Tetsuro Urushidani -- Relationship between N-acetyltransferase-2 gene polymorphism and isoniazid-induced hepatotoxicity / Yasuo Shimazu, Kunio Dobashi and Masatomo Mori -- Human and animal-based differences in hepatic xenobiotic metabolism and toxicity / Peter J. O'Brien, Katie Chan and Raymond J. Poon -- Hepatotoxicity in oncology drug development / Wei Chen, Kenneth Hastings, and John K. Leighton -- The potent rat hepatocarcinogen methapyrilene: an hypothesis regarding its hepatotoxicology / Daniel A. Casciano -- Botanical supplements and hepatotoxicity / Shabana Khan, Ikhlas Khan and Larry Walker -- Physiologically based pharmokinetic modelling and risk assessment of hepatotoxicants / Kannan Krishnan.
650 1 2 $a Drug-Induced Liver Injury $x etiology $3 302783
650 2 2 $a Drug Evaluation, Preclinical $3 302784
650 2 2 $2 96060 $a Liver $x drug effects $3 247001
650 2 2 $a Models, Biological $3 302785
650 2 2 $a Toxicogenetics $x methods $3 302786