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Molecular biology in medicinal chemi...

Molecular biology in medicinal chemistry /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Molecular biology in medicinal chemistry // edited by Th. Dingermann, D. Steinhilber and G. Folkers
出版者:	Weinheim :Wiley-VCH, : 2003,
版本:	1. Aufl
面頁冊數:	xxi, 413 p. :ill. ; : 24 cm;
提要註:	Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action
叢書名:	Methods and principles in medical chemistry ;
標題:	MOLECULAR BIOLOGY. -
ISBN:	3527304312 (hard):

Molecular biology in medicinal chemistry /
Molecular biology in medicinal chemistry /edited by Th. Dingermann, D. Steinhilber and G. Folkers - 1. Aufl - Weinheim :Wiley-VCH,2003 - xxi, 413 p. :ill. ;24 cm - Methods and principles in medical chemistry ;v. 21.

Includes bibliographical references and index

Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potentialof orphan GPCRs -- Stereoselective synthesis with the helpof recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N-Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology

Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action

ISBN: 3527304312 (hard):NT5185Subjects--Topical Terms:

188044
MOLECULAR BIOLOGY.

National Library of Medicine Call No.: QU25 / M718

Molecular biology in medicinal chemistry /
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245 0 0 $a Molecular biology in medicinal chemistry / $c edited by Th. Dingermann, D. Steinhilber and G. Folkers
250 $a 1. Aufl
260 # $a Weinheim : $c 2003 $b Wiley-VCH,
300 $a xxi, 413 p. : $b ill. ; $c 24 cm
440 0 $a Methods and principles in medical chemistry ; $v v. 21
504 $a Includes bibliographical references and index
505 0 # $a Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potentialof orphan GPCRs -- Stereoselective synthesis with the helpof recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N-Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology
520 # $a Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action
650 # 0 $2 96060 $a MOLECULAR BIOLOGY. $3 188044
650 # 0 $2 96060 $a Chiral drugs. $3 214167
650 # 0 $2 96060 $a Genomics $x Automation $3 221589
650 # 0 $2 96060 $a Pharmacogenomics $3 226533
650 # 0 $2 96060 $a Molecular pharmacology $3 226532
900 $c 到館:2005/05/16 $d 編目:2005/05/16