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Drug transporters

Fromm, Martin F.

Drug transporters

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Drug transporters/ Martin F. Fromm, Richard B. Kim, editors.
其他作者:	Fromm, Martin F.
出版者:	Heidelberg ;Springer-Verlag Berlin Heidelberg, : c2011.,
面頁冊數:	1 online resource (x, 454 p.) :ill. (some col.) :
提要註:	It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.
標題:	Carrier proteins. -
電子資源:	http://public.eblib.com/EBLPublic/PublicView.do?ptiID=645797
ISBN:	9783642145414 (electronic bk.)

Drug transporters
Drug transporters[electronic resource] /Martin F. Fromm, Richard B. Kim, editors. - Heidelberg ;Springer-Verlag Berlin Heidelberg,c2011. - 1 online resource (x, 454 p.) :ill. (some col.) - Handbook of experimental pharmacology ;v. 201. - Handbook of experimental pharmacology ;v. 201..

Includes bibliographical references and index.

Drug Transporters; Preface; Contents; Contributors; Uptake Transporters of the Human OATP Family; In Vitro and In Vivo Evidence of the Importance of Organic Anion Transporters (OATs) in Drug Therapy; Organic Cation Transporters (OCTs, MATEs), In Vitro and In Vivo Evidence for the Importance in Drug Therapy; Role of the Intestinal Bile Acid Transporters in Bile Acid and Drug Disposition; The Role of the Sodium-Taurocholate Cotransporting Polypeptide (NTCP) and of the Bile Salt Export Pump (BSEP) in Physiology and Pathophysiology of Bile Formation.

It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.

ISBN: 9783642145414 (electronic bk.)

Source: 978-3-642-14540-7Springerhttp://www.springerlink.com

Nat. Bib. Agency Control No.: 015740258UkSubjects--Topical Terms:

254781
Carrier proteins.
Index Terms--Genre/Form:

228523
Electronic books.

LC Class. No.: QP552.C34 / D78 2011

Dewey Class. No.: 572/.696

Drug transporters
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520 $a It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.
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