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Capillary electrophoresis methods fo...

Ahuja, Satinder, (1933-)

Capillary electrophoresis methods for pharmaceutical analysis

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Capillary electrophoresis methods for pharmaceutical analysis/ edited by Satinder Ahuja, M. llias Jimidar.
其他作者:	Ahuja, Satinder,
出版者:	Amsterdam ;Elsevier/Academic Press, : 2008.,
版本:	1st ed.
面頁冊數:	xvi, 529 p. :ill. :
提要註:	Capillary electrophoresis (CE) is a powerful analytical technique that is widely used in research and development and in quality control of pharmaceuticals. Many reports of highly efficient separations and methods have been published over the past 15 years. CE offers several advantages over high-pressure or high-performance liquid chromatography (HPLC). These include simplicity, rapid analysis, automation, ruggedness, different mechanisms for selectivity, and low cost. Moreover, EC requires smaller sample size and yet offers higher efficiency and thus greater resolution power over HPLC. These characteristics are very attractive in research and development, even more so in pharmaceutical quality control (QC) and stability monitoring (SM) studies. This book will provide busy pharmaceutical scientists a complete yet concise reference guide for utilizing the versatility of CE in new drug development and quality control. - Provides current status and future developments in CE analysis of pharmaceuticals. - Explains how to develop and validate methods. - Includes major pharmaceutical applications including assays and impurity testing.
標題:	Electrophoresis, Capillary - methods. -
電子資源:	http://www.sciencedirect.com/science/book/9780123725738
ISBN:	9780123725738

Capillary electrophoresis methods for pharmaceutical analysis
Capillary electrophoresis methods for pharmaceutical analysis[electronic resource] /edited by Satinder Ahuja, M. llias Jimidar. - 1st ed. - Amsterdam ;Elsevier/Academic Press,2008. - xvi, 529 p. :ill. - Separation science and technology,v. 90149-6395 ;. - Separation science and technology (San Diego, Calif.) ;v. 9..

Includes bibliographical references and index.

Preface -- 1. Overview of Capillary Electrophoresis in Pharmaceutical Analysis -- 2. Theoretical Consideration in Performance of Various Modes of CE -- 3. Equipment Considerations for Capillary Electrophoresis -- 4. Method Development for Pharmaceutical Analysis -- 5. Role of CE in Drug Substance and Drug Product Development -- 6. General Considerations to Improve Performance of CE Methods -- 7. Overview of Current Regulatory Guidance -- 8. Qualification of CE Instrumentation -- 9. Robustness Testing of CE Methods -- 10. Validation of Analytical Methods -- 11. The Need for CE Methods in Pharmacopeial Monographs -- 12. CE in Impurity Profiling of Drugs -- 13. Ion Analysis -- 14. Role of CE in Biopharmaceutical Development and Quality Control -- 15. Capillary Electrophoresis and Bioanalysis -- 16. CE as Orthogonal Technique to Chromatography -- 17. Capillary Electrochromatography of Pharmaceuticals -- 18. Coupling CE and Chip-based Devices and Mass Spectrometry.

Capillary electrophoresis (CE) is a powerful analytical technique that is widely used in research and development and in quality control of pharmaceuticals. Many reports of highly efficient separations and methods have been published over the past 15 years. CE offers several advantages over high-pressure or high-performance liquid chromatography (HPLC). These include simplicity, rapid analysis, automation, ruggedness, different mechanisms for selectivity, and low cost. Moreover, EC requires smaller sample size and yet offers higher efficiency and thus greater resolution power over HPLC. These characteristics are very attractive in research and development, even more so in pharmaceutical quality control (QC) and stability monitoring (SM) studies. This book will provide busy pharmaceutical scientists a complete yet concise reference guide for utilizing the versatility of CE in new drug development and quality control. - Provides current status and future developments in CE analysis of pharmaceuticals. - Explains how to develop and validate methods. - Includes major pharmaceutical applications including assays and impurity testing.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2008.

Mode of access: World Wide Web.

ISBN: 9780123725738

Source: 133709:133834Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

217543
Electrophoresis, Capillary
--methods.Index Terms--Genre/Form:

228523
Electronic books.

LC Class. No.: RS189.5.C34 / C375 2008eb

Dewey Class. No.: 615.90101541372

National Library of Medicine Call No.: 2008 K-371

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