高雄醫學大學圖書館 |

語系/ Language: 繁體中文

登入

回首頁

Clinical pharmacokinetics and pharma...

Rowland, Malcolm.

Clinical pharmacokinetics and pharmacodynamics :concepts and applications /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Clinical pharmacokinetics and pharmacodynamics :/ Malcolm Rowland, Thomas N. Tozer.
其他題名:	concepts and applications /
作者:	Rowland, Malcolm.
其他作者:	Rowland, Malcolm.
出版者:	Philadelphia :Wolters Kluwer Health/Lippincott William & Wilkins, : c2011.,
版本:	4th ed.
面頁冊數:	xxii, 839 p. :ill. ; : 26 cm.;
附註:	Rev. ed. of: Clinical pharmacokinetics. 1995.
提要註:	"Formerly Clinical Pharmacokinetics: Concepts and Applications, this fully updated Fourth Edition has been retitled Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This revised edition also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs. The text is authored by two leading international experts on the clinical aspects of pharmacokinetics/pharmacodynamics and is widely considered one of the authoritative texts on the subject."--BOOK JACKET.
標題:	Drug Therapy. -
ISBN:	978-0-7817-5009-7 (hard) :

Clinical pharmacokinetics and pharmacodynamics :concepts and applications /
Rowland, Malcolm.

Clinical pharmacokinetics and pharmacodynamics :concepts and applications /Malcolm Rowland, Thomas N. Tozer. - 4th ed. - Philadelphia :Wolters Kluwer Health/Lippincott William & Wilkins,c2011. - xxii, 839 p. :ill. ;26 cm.

Rev. ed. of: Clinical pharmacokinetics. 1995.

Includes bibliographical references and index.

Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple-dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.

"Formerly Clinical Pharmacokinetics: Concepts and Applications, this fully updated Fourth Edition has been retitled Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This revised edition also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs. The text is authored by two leading international experts on the clinical aspects of pharmacokinetics/pharmacodynamics and is widely considered one of the authoritative texts on the subject."--BOOK JACKET.

ISBN: 978-0-7817-5009-7 (hard) :NT2264

LCCN: 2009028928Subjects--Topical Terms:

218675
Drug Therapy.

LC Class. No.: RM301.5 / .R68 2011

National Library of Medicine Call No.: 2010 I-082

Clinical pharmacokinetics and pharmacodynamics :concepts and applications /
LDR:02259cam a2200301 a 4500 001 253956
003 OCoLC
005 20121221034548.0
008 130114s2011 paua 001 0 eng
010 $a 2009028928
019 $a 149457784
020 $a 978-0-7817-5009-7 (hard) : $c NT2264
020 $a 0-7817-5009-1
035 $a (OCoLC)426115435 $z (OCoLC)149457784
035 $a 27350000001
040 $a KMU $b KMU
049 $a FISA
050 0 0 $a RM301.5 $b .R68 2011
060 0 0 $a 2010 I-082
060 1 0 $a QV38 $b R883 2011
100 1 $a Rowland, Malcolm. $3 293062
245 1 0 $a Clinical pharmacokinetics and pharmacodynamics : $b concepts and applications / $c Malcolm Rowland, Thomas N. Tozer.
250 $a 4th ed.
260 $a Philadelphia : $c c2011. $b Wolters Kluwer Health/Lippincott William & Wilkins,
300 $a xxii, 839 p. : $b ill. ; $c 26 cm.
500 $a Rev. ed. of: Clinical pharmacokinetics. 1995.
500 $a Includes index.
504 $a Includes bibliographical references and index.
505 0 $a Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple-dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.
520 1 $a "Formerly Clinical Pharmacokinetics: Concepts and Applications, this fully updated Fourth Edition has been retitled Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This revised edition also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs. The text is authored by two leading international experts on the clinical aspects of pharmacokinetics/pharmacodynamics and is widely considered one of the authoritative texts on the subject."--BOOK JACKET.
650 2 2 $2 96060 $a Drug Therapy. $3 218675
650 0 $2 96060 $a Chemotherapy. $3 212759
650 0 $2 96060 $a Pharmacokinetics. $3 194144
700 1 $a Rowland, Malcolm. $3 293062
700 1 $2 97000 $a Tozer, Thomas N. $3 189350