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Affinity and efficacythe components ...

Ehlert, Frederick J.

Affinity and efficacythe components of drug-receptor interactions /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Affinity and efficacy/ Frederick J. Ehlert.
其他題名:	the components of drug-receptor interactions /
其他題名:	Components of drug-receptor interactions
作者:	Ehlert, Frederick J.
出版者:	New Jersey :World Scientific, : 2014.,
面頁冊數:	1 online resource.
標題:	Receptors, G-Protein-Coupled. -
電子資源:	http://www.worldscientific.com/worldscibooks/10.1142/7888#t=toc
ISBN:	9789814324229

Affinity and efficacythe components of drug-receptor interactions /
Ehlert, Frederick J.

Affinity and efficacythe components of drug-receptor interactions /[electronic resource] :Components of drug-receptor interactionsFrederick J. Ehlert. - New Jersey :World Scientific,2014. - 1 online resource.

Includes bibliographical references.

Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors.

ISBN: 9789814324229Subjects--Topical Terms:

255128
Receptors, G-Protein-Coupled.

LC Class. No.: RM302.4

Dewey Class. No.: 615.7/0452

National Library of Medicine Call No.: QV 36

Affinity and efficacythe components of drug-receptor interactions /
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100 1 $a Ehlert, Frederick J. $3 382728
245 1 0 $a Affinity and efficacy $h [electronic resource] : $b the components of drug-receptor interactions / $c Frederick J. Ehlert.
246 1 $a Components of drug-receptor interactions
260 $a New Jersey : $c 2014. $b World Scientific,
300 $a 1 online resource.
504 $a Includes bibliographical references.
505 0 $a Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors.
588 0 $a Print version record.
650 2 2 $2 96060 $a Receptors, G-Protein-Coupled. $3 255128
650 2 2 $a Radioligand Assay. $3 382734
650 2 2 $2 96060 $a Protein Binding. $3 254774
650 2 2 $a Ligand-Gated Ion Channels. $3 382733
650 1 2 $a Receptors, Drug. $3 382732
650 0 $2 96060 $a Pharmaceutical chemistry. $3 240627
650 0 $a Drug-nutrient interactions. $3 382731
650 0 $a Drugs $x Effectiveness. $3 382730
650 0 $a Drug receptors. $3 382729
856 4 0 $u http://www.worldscientific.com/worldscibooks/10.1142/7888#t=toc

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