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金屬奈米材料合成及其食品污染物SERS之檢測 = Synthesis o...

金屬奈米材料合成及其食品污染物SERS之檢測 = Synthesis of Metal Nanomaterials and their SERS Detection for Food Contaminants

紀錄類型:	書目-語言資料,印刷品 : 單行本
並列題名:	Synthesis of Metal Nanomaterials and their SERS Detection for Food Contaminants
出版地:	[高雄市]
出版者:	[撰者];
出版年:	2023[民112]
面頁冊數:	109葉圖 : 30公分;
標題:	Cysteine functionalized
電子資源:	https://handle.ncl.edu.tw/11296/4ezxp2
內容註:	Table of Contents

金屬奈米材料合成及其食品污染物SERS之檢測 = Synthesis of Metal Nanomaterials and their SERS Detection for Food Contaminants
金屬奈米材料合成及其食品污染物SERS之檢測 = Synthesis of Metal Nanomaterials and their SERS Detection for Food Contaminants / SANDHIYA DAYALAN - [高雄市] : [撰者], 2023[民112]. - 109葉 ; 圖 ; 30公分.
Table of Contents .
參考書目: 葉.
Cysteine functionalized

金屬奈米材料合成及其食品污染物SERS之檢測 = Synthesis of Metal Nanomaterials and their SERS Detection for Food Contaminants
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200 1 $a 金屬奈米材料合成及其食品污染物SERS之檢測 $d Synthesis of Metal Nanomaterials and their SERS Detection for Food Contaminants $z eng $f SANDHIYA DAYALAN
210 $a [高雄市] $c [撰者] $d 2023[民112]
215 0 $a 109葉 $c 圖 $d 30公分
314 $a 指導教授: 黃俊嬴
320 $a 參考書目: 葉
327 1 $a Table of Contents
328 $a 博士論文--高雄醫學大學醫藥暨應用化學系博士班
330 $u Food contamination involves the presence of toxic microorganisms and chemicals in food that can cause illness in consumers. A Raman spectroscopy paired with a highly repeatable surface-enhanced Raman scattering (SERS) substrate was used to evaluate a range of food contaminants, including food‒borne pathogens and pesticides, due to its high sensitivity and fingerprinting recognition efficiencies. Plasmonic nanoparticles (Au and Ag) can be used to detect food contaminants in food matrices. In these studies, different nanomaterial / SERS substrates were developed through seed-mediated methods. Firstly, Au seeds were prepared through biological and chemical methods. Subsequently, the prepared Au seeds were used to grow different nanoparticles including gold nanostars (GNSs) and bimetallic core-shell nanoparticles (Au@AgNPs), which were then applied for the detection of food contaminants. GNSs were functionalized with vancomycin (GNSs-4-MBA-van) and used as a SERS tag for specific and sensitive quantification of food pathogens. The Raman reporter molecule 4- mercaptobenzoic acid (4-MBA) was also used as a linker molecule to attach vancomycin over gold nanostars (GNSs). The SERS impact of cysteine-functionalized bimetallic core-shell nanoparticles (Au@Ag@CysNPs) substrates with different pH treatments on pesticide compounds was examined. Due to GNSs-based SERS enhancement and vancomycin-based bacterial recognition ability, a detection limit of 5.7 CFU/ mL and 8.3 CFU/ mL, were achieved for S. aureus and E. coli, respectively. A principal component analysis (PCA) method was used to discriminate the two pathogens by the reproducible and specific intrinsic fingerprint and intracellular component obtained by SERS. Moreover, the spiked test results showed that GNSs-4-MBA-van is valid as a potential biosensor for detecting pathogens in the fresh meat and food processing industries. The pH-dependent SERS impact of Au@Ag@CysNPs on detecting pesticide compounds exhibited different enhancements over the pH range of 2-11 and exited the highest enhancement at a pH of 5 for thiabendazole and thiram pesticides. The prepared Au@Ag@CysNPs were further utilized in SERS-based rapid detection of pesticides on apple peels by directly dropping Au@Ag@CysNPs on the samples’ surface, where the target molecules could be identified without elution or extraction. These findings revealed that this Au@Ag@CysNPs substrate exhibited excellent SERS performances for pesticide compounds as well as good stability. With the additional optimization, detection limits of 10 ng/cm2 for thiabendazole (Tbz) and thiram were both obtained.
510 1 $a Synthesis of Metal Nanomaterials and their SERS Detection for Food Contaminants $z eng
610 # 1 $a Cysteine functionalized $a Vancomycin functionalized $a Pesticides $a Food-borne Pathogen $a Food contaminants $a SERS detection $a Nanomaterial synthesis $a Gold nanostars $a Bimetallic nanoparticles
856 4 # $u https://handle.ncl.edu.tw/11296/4ezxp2 $z 電子資源