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Osteoimmunologyinteractions of the immune and skeletal systems /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Osteoimmunology/ edited by Joseph Lorenzo ... [et al.].
其他題名:	interactions of the immune and skeletal systems /
其他作者:	Lorenzo, Joseph.
出版者:	Amsterdam ;Academic, : 2011.,
版本:	1st ed.
面頁冊數:	xiii, 453 p., [20] p. of plates :ill. (some col.) ; : 25 cm.;
提要註:	Bone and the immune system are both complex tissues, which, respectively, regulate the skeleton and the body's responses to invading pathogens. It has become increasingly clear that critical interactions between these two organ systems frequently occur. This is particularly true for the development of immune cells in the bone marrow and for the function of bone cells in health and disease. However, because these two disciplines developed independently, investigators in each don't always fully appreciate the significance of the other. This book is meant to provide a detailed overview of the many ways that bone and immune cells interact. The goal is to provide basic and clinical scientists with a better understanding of the role that the immune system and bone play in the development and function of each other so that advances in both fields will be facilitated. The focus of the book will be both on basic pathways and translational science, which will apply basic knowledge to clinical diseases. Chapter content will range from basic descriptions of the various cell systems and their development to the signals that cause them to interact during normal physiology and disease. Approximately half the book will focus on the role that osteoimmunology plays in the development of human diseases. This is a rapidly developing area that is of interest to a wide spectrum of researchers, students, and fellows in immunology, rheumatology, hematology, and bone biology - all of whom need to develop a more complete understanding of their previously separate disciplines and the mechanisms by which they interact.
標題:	Bone - Physiology. -
電子資源:	An electronic book accessible through the World Wide Web; click for information
ISBN:	9780123756701

Osteoimmunologyinteractions of the immune and skeletal systems /
Osteoimmunologyinteractions of the immune and skeletal systems /[electronic resource] :edited by Joseph Lorenzo ... [et al.]. - 1st ed. - Amsterdam ;Academic,2011. - xiii, 453 p., [20] p. of plates :ill. (some col.) ;25 cm.

Includes bibliographical references and index.

Overview: The developing Field of Osteoimmunology / Yongwon Choi, Mark Horowitz, Hiroshi Takayanagi, Joseph Lorenzo -- The Origins of Bone Cells: Osteoclasts / G. David Roodman, Deborah L. Galson -- Adaptive Immune Response / David G. Hesslein, Hector L. Aguila, Mark C. Horowitz -- The Role of Bone Cells in Establishing the Hematopoietic Stem Cell Niche / Henry Kronenberg, Joy Wu -- The Signaling Pathways Regulating Osteoblast Differentiation / Jane Lian, Gary Stein -- The Signaling Pathways Regulating Osteoclast Differentiation / Steven Teitelbaum, Roberta Faccio, Hiroshi Takayanagi, Yongwon Choi -- The Effects of Immune Cells Products (Cytokines and Growth Factors) on Bone Cells / Joseph Lorenzo -- Interactions of Osteoblasts and Osteoclasts / T. John Martin, Natalie A. Sims, Julian M. W. Quinn -- The Role of the Immune System in the Development of Osteoporosis / Sundeep Khosla, B. Lawrence Riggs, Ulrike I. Moedder -- The Role of the Immune System in the Bone Loss of Inflammatory Arthritis / Georg Schett, Steven Goldring -- The Role of the Immune System in the Bone Loss of Inflammatory Bowel Disease / Francisco Sylvester, Anthony T. Vella -- The Role of the Immune System in Fracture Healing / Louis Gerstenfeld, Thomas Einhorn, Brandon Steen -- The Role of the Immune System in the Development of Chronic Infections of Bone / Brendan Boyce, Edward Schwarz, Lianping Xing -- The Role of the Immune System in Hematologic Malignancies, which Affect Bone / Gregory Mundy, Claire M. Edwards, Jessica Fowler -- The Role of the Immune System in Dental Disease / Dana Graves, Rayyan A. Kayal, Thomas Oates, Gustavo Garlet.

Bone and the immune system are both complex tissues, which, respectively, regulate the skeleton and the body's responses to invading pathogens. It has become increasingly clear that critical interactions between these two organ systems frequently occur. This is particularly true for the development of immune cells in the bone marrow and for the function of bone cells in health and disease. However, because these two disciplines developed independently, investigators in each don't always fully appreciate the significance of the other. This book is meant to provide a detailed overview of the many ways that bone and immune cells interact. The goal is to provide basic and clinical scientists with a better understanding of the role that the immune system and bone play in the development and function of each other so that advances in both fields will be facilitated. The focus of the book will be both on basic pathways and translational science, which will apply basic knowledge to clinical diseases. Chapter content will range from basic descriptions of the various cell systems and their development to the signals that cause them to interact during normal physiology and disease. Approximately half the book will focus on the role that osteoimmunology plays in the development of human diseases. This is a rapidly developing area that is of interest to a wide spectrum of researchers, students, and fellows in immunology, rheumatology, hematology, and bone biology - all of whom need to develop a more complete understanding of their previously separate disciplines and the mechanisms by which they interact.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2010.

Mode of access: World Wide Web.

ISBN: 9780123756701

Source: 1010924:10109121Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

306829
Bone
--Physiology.Index Terms--Genre/Form:

228523
Electronic books.

LC Class. No.: QP88.2 / .O88 2011

Dewey Class. No.: 616.7079

Osteoimmunologyinteractions of the immune and skeletal systems /
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504 $a Includes bibliographical references and index.
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520 $a Bone and the immune system are both complex tissues, which, respectively, regulate the skeleton and the body's responses to invading pathogens. It has become increasingly clear that critical interactions between these two organ systems frequently occur. This is particularly true for the development of immune cells in the bone marrow and for the function of bone cells in health and disease. However, because these two disciplines developed independently, investigators in each don't always fully appreciate the significance of the other. This book is meant to provide a detailed overview of the many ways that bone and immune cells interact. The goal is to provide basic and clinical scientists with a better understanding of the role that the immune system and bone play in the development and function of each other so that advances in both fields will be facilitated. The focus of the book will be both on basic pathways and translational science, which will apply basic knowledge to clinical diseases. Chapter content will range from basic descriptions of the various cell systems and their development to the signals that cause them to interact during normal physiology and disease. Approximately half the book will focus on the role that osteoimmunology plays in the development of human diseases. This is a rapidly developing area that is of interest to a wide spectrum of researchers, students, and fellows in immunology, rheumatology, hematology, and bone biology - all of whom need to develop a more complete understanding of their previously separate disciplines and the mechanisms by which they interact.
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