高雄醫學大學圖書館 |

語系/ Language: 繁體中文

登入

回首頁 到查詢結果 [ subject:"Pharmacology/Toxicology." ]

Molecular targeted radiosensitizerso...

Eke, Iris.

Molecular targeted radiosensitizersopportunities and challenges /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Molecular targeted radiosensitizers/ edited by Henning Willers, Iris Eke.
其他題名:	opportunities and challenges /
其他作者:	Eke, Iris.
出版者:	Cham :Springer International Publishing : : 2020.,
面頁冊數:	xi, 364 p. :ill., digital ; : 24 cm.;
提要註:	Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.
Contained By:	Springer Nature eBook
標題:	Pharmacology/Toxicology. -
電子資源:	https://doi.org/10.1007/978-3-030-49701-9
ISBN:	9783030497019

Molecular targeted radiosensitizersopportunities and challenges /
Molecular targeted radiosensitizersopportunities and challenges /[electronic resource] :edited by Henning Willers, Iris Eke. - Cham :Springer International Publishing :2020. - xi, 364 p. :ill., digital ;24 cm. - Cancer drug discovery and development,2196-9906. - Cancer drug discovery and development..

Introduction to Molecular Targeted Radiosensitizers: Opportunities and Challenges -- Translating Targeted Radiosensitizers into the Clinic -- Cartography of the Radiogenome of Human Cancers -- Mechanisms and Markers of Clinical Radioresistance -- Preclinical Strategies for Testing of Targeted Radiosensitizers -- 3D Radiation Biology for Identifying Radiosensitizers -- Preclinical in vivo evaluation of novel radiosensitizers by local tumor control experiments -- Genetically Engineered Mouse Models for Studying Radiation Biology and Radiosensitizers -- Targeting the DNA Damage Response for Radiosensitization -- Targeting Tumor Metabolism to Overcome Radioresistance -- Targeting Tumor Hypoxia -- Normalizing the Tumor Microenvironment for Radiosensitization -- Radiosensitizers in the Era of Immuno-Oncology -- Index.

Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.

ISBN: 9783030497019

Standard No.: 10.1007/978-3-030-49701-9doiSubjects--Topical Terms:

465008
Pharmacology/Toxicology.

LC Class. No.: RC271.R3 / M654 2020

Dewey Class. No.: 616.9940642

Molecular targeted radiosensitizersopportunities and challenges /
LDR:03366nam a2200337 a 4500 001 338296
003 DE-He213
005 20201229094639.0
006 m d
007 cr nn 008maaau
008 210622s2020 sz s 0 eng d
020 $a 9783030497019 $q (electronic bk.)
020 $a 9783030497002 $q (paper)
024 7 $a 10.1007/978-3-030-49701-9 $2 doi
035 $a 978-3-030-49701-9
040 $a GP $c GP
041 0 $a eng
050 4 $a RC271.R3 $b M654 2020
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 616.9940642 $2 23
090 $a RC271.R3 $b M718 2020
245 0 0 $a Molecular targeted radiosensitizers $h [electronic resource] : $b opportunities and challenges / $c edited by Henning Willers, Iris Eke.
260 $a Cham : $b Springer International Publishing : $b Imprint: Humana, $c 2020.
300 $a xi, 364 p. : $b ill., digital ; $c 24 cm.
490 1 $a Cancer drug discovery and development, $x 2196-9906
505 0 $a Introduction to Molecular Targeted Radiosensitizers: Opportunities and Challenges -- Translating Targeted Radiosensitizers into the Clinic -- Cartography of the Radiogenome of Human Cancers -- Mechanisms and Markers of Clinical Radioresistance -- Preclinical Strategies for Testing of Targeted Radiosensitizers -- 3D Radiation Biology for Identifying Radiosensitizers -- Preclinical in vivo evaluation of novel radiosensitizers by local tumor control experiments -- Genetically Engineered Mouse Models for Studying Radiation Biology and Radiosensitizers -- Targeting the DNA Damage Response for Radiosensitization -- Targeting Tumor Metabolism to Overcome Radioresistance -- Targeting Tumor Hypoxia -- Normalizing the Tumor Microenvironment for Radiosensitization -- Radiosensitizers in the Era of Immuno-Oncology -- Index.
520 $a Molecular Targeted Radiosensitizers: Opportunities and Challenges provides the reader with a comprehensive review of key pre-clinical research components required to identify effective radiosensitizing drugs. The book features discussions on the mechanisms and markers of clinical radioresistance, pre-clinical screening of targeted radiosensitizers, 3D radiation biology for studying radiosensitizers, in vivo determinations of local tumor control, genetically engineered mouse models for studying radiosensitizers, targeting the DNA damage response for radiosensitization, targeting tumor metabolism to overcome radioresistance, radiosensitizers in the era of immuno-oncology, and more. Additionally, the book features discussions on high-throughput drug screening, predictive biomarkers, pre-clinical tumor models, and the influence of the tumor microenvironment and the immune system, with a specific focus on the challenges radiation oncologists and medical oncologists currently face in testing radiosensitizers in human cancers. Edited by two acclaimed experts in radiation biology and radiosensitizers, with thirteen chapters contributed by experts, this new volume presents an in-depth look at current developments within a rapidly moving field, with a look at where the field will be heading and providing comprehensive insight into the framework of targeted radiosensitzer development. Essential reading for investigators in cancer research and radiation biology.
650 2 4 $a Pharmacology/Toxicology. $3 465008
650 2 4 $2 96060 $a Radiotherapy. $3 254565
650 1 4 $a Cancer Research. $3 465286
650 0 $a Radiation-sensitizing agents. $3 466198
650 0 $a Cancer $x Radiotherapy $x Molecular aspects. $3 466197
700 1 $a Eke, Iris. $3 466196
700 1 $a Willers, Henning. $3 466195
710 2 $2 97100 $a SpringerLink (Online service) $3 255133
773 0 $t Springer Nature eBook
830 0 $a Cancer drug discovery and development. $3 283948
856 4 0 $u https://doi.org/10.1007/978-3-030-49701-9
950 $a Medicine (SpringerNature-11650)

筆 0 讀者評論

多媒體

評論

新增評論分享你的心得，請勿在此評論區張貼涉及人身攻擊、情緒謾罵、或內容涉及非法的不當言論，館方有權利刪除任何違反評論規則之發言，情節嚴重者一律停權，以維護所有讀者的自由言論空間。

Export

取書館別