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The epigenome and developmental orig...
Rosenfeld, Cheryl S.

 

  • The epigenome and developmental origins of health and disease
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    正題名/作者: The epigenome and developmental origins of health and disease/ edited by Cheryl S. Rosenfeld.
    其他作者: Rosenfeld, Cheryl S.
    出版者: Amsterdam :Academic Press, : c2015.,
    面頁冊數: 1 online resource (xvii, 542 p.) :ill. (chielfly col.) :
    提要註: "The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or conversely promote the health of the offspring. This book mines the existing literature of a variety of disciplines, from toxicology to nutrition to epigenetics, to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother's diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of ourchildren, possibly leading to metabolic, cardiovascular, immunological, and neurobehavioral disorders, and increased risk of cancer, to list but a few examples. Importantly, the common thread of how in utero and postnatal environmental changes may lead to DOHaD effects is through various epigenetic changes. The Epigenome and Developmental Origins of Health and Disease is a unique resource not only for geneticists and epigeneticists, but also for toxicologists, obestetricians, gynecologists, neurobiologists, nutritionists, physiologists, and psychologists."--Page 4 of cover
    標題: Epigenetics. -
    電子資源: click for full text
    ISBN: 9780128013830 (electronic bk.)
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