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Clinical pharmacokinetics and pharma...

Rowland, Malcolm.

Clinical pharmacokinetics and pharmacodynamics :concepts and applications /

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Clinical pharmacokinetics and pharmacodynamics :/ Malcolm Rowland and Thomas N. Tozer.
Reminder of title:	concepts and applications /
Author:	Rowland, Malcolm.
other author:	Rowland, Malcolm.
Published:	Philadelphia :Wolters Kluwer Health/Lippincott William & Wilkins, : c2011.,
[NT 15000922]:	4th ed.
Description:	xxii, 839 p. :ill., ports. :
Notes:	Rev. ed. of: Clinical pharmacokinetics. 1995.
Subject:	Drug Therapy -
ISBN:	9780781750097

Clinical pharmacokinetics and pharmacodynamics :concepts and applications /
Rowland, Malcolm.

Clinical pharmacokinetics and pharmacodynamics :concepts and applications /Malcolm Rowland and Thomas N. Tozer. - 4th ed. - Philadelphia :Wolters Kluwer Health/Lippincott William & Wilkins,c2011. - xxii, 839 p. :ill., ports.

Rev. ed. of: Clinical pharmacokinetics. 1995.

Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.

ISBN: 9780781750097

LCCN: 2009028928Subjects--Topical Terms:

234848
Drug Therapy

National Library of Medicine Call No.: 2010 I-082

Clinical pharmacokinetics and pharmacodynamics :concepts and applications /
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100 1 $a Rowland, Malcolm. $3 293062
245 1 0 $a Clinical pharmacokinetics and pharmacodynamics : $b concepts and applications / $c Malcolm Rowland and Thomas N. Tozer.
250 $a 4th ed.
260 $a Philadelphia : $c c2011. $b Wolters Kluwer Health/Lippincott William & Wilkins,
300 $a xxii, 839 p. : $b ill., ports.
500 $a Rev. ed. of: Clinical pharmacokinetics. 1995.
505 0 $a Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.
650 2 2 $2 96060 $a Drug Therapy $3 234848
650 1 2 $2 96060 $a Pharmacokinetics $3 192803
700 1 $a Rowland, Malcolm. $3 293062
700 1 $2 97000 $a Tozer, Thomas N. $3 189350
963 $a Katy Whipple; phone: 240-295-5682; email: kwhipple@marylandcomp.com; bc: betsy.gentzler@wolterskluwer.com
992 $p P1 $e EF $a 20100812
993 $a EJP $b 20090714
994 $a [CDN] $b [date: YYYYMMDD]***To be added at rev. CIP process
995 $a AUTH $b 20090714 $c REV $d 20091028
996 $a [ACTION] $b YYYYMMDD (CMU inputs)
997 $a TO LC: Prev. ed. LCCN: 94026305. $5 DLC
997 $a VERIFIER: per change request, 9/9/09, title changed (from: Pharmacokinetics and pharmacodynamics). Confirm upon receipt.
997 $a VERIFIER: per change request, 9/22/09, subtitle changed (from: concepts and clinical applications). Confirm upon receipt.
997 $a VERIFIER: per change request, 10/28/09, author Tozer's name will appear in full on t.p. (was: Tom Tozer). Confirm upon receipt.
999 $a WTC