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Drug discriminationapplications to medicinal chemistry and drug studies /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Drug discrimination/ edited by Richard A. Glennon, Virginia Commonwealth University, Richard Young, Virginia Commonwealth University.
其他題名:	applications to medicinal chemistry and drug studies /
其他作者:	Glennon, Richard A.,
出版者:	Hoboken, N.J. :Wiley, : c2011.,
面頁冊數:	1 online resource (xx, 510 p.) :ill. :
提要註:	Although somewhat labor intensive, Drug Discrimination (DD) is of enormous applicability to the understanding of drug action. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies covers the practical applications of drug discrimination studies for medicinal chemistry, including strengths and limitations versus other pharmacological methods for evaluating drug action. The book provides medicinal chemists with a fuller understanding of the nature and use of drug discrimination studies for evaluating the action of drugs while helping pharmacologists understand and better interact with medicinal chemists and drug designers when sharing pharmacologic data.
標題:	Drug discrimination (Pharmacology) -
電子資源:	http://site.ebrary.com/id/10494666
ISBN:	9781118023150 (electronic bk.)

Drug discriminationapplications to medicinal chemistry and drug studies /
Drug discriminationapplications to medicinal chemistry and drug studies /[electronic resource] :edited by Richard A. Glennon, Virginia Commonwealth University, Richard Young, Virginia Commonwealth University. - Hoboken, N.J. :Wiley,c2011. - 1 online resource (xx, 510 p.) :ill.

Includes bibliographical references and index.

Frontmatter -- Color Plates -- Part I. Part Introduction -- An Introduction to Drug Discrimination -- Methodological Considerations -- Drug Discrimination: Practical Considerations -- Role of Stereochemistry in Drug Discrimination Studies -- Drug Discrimination and In Vivo Structure b6 sActivity Relationships -- Drug Discrimination and Mechanisms of Drug Action -- Drug Discrimination and Development of Novel Agents and Pharmacological Tools -- Appendix -- Part II. Part Introduction -- Perceptual Drug Discriminative Aspects of the Endocannabinoid Signaling System in Animals And Man / Torb�jrn U C �Jrbe -- Discriminative Stimulus Properties of Receptor Antagonists / Joseph H Porter -- The Discrimination of Drug Mixtures / Ian P Stolerman -- Making the Right Choice: Lessons From Drug Discrimination for Research on Drug Reinforcement And Drug Self-Administration / S Stevens Negus, Matthew L Banks -- Inhalant Drug Discrimination: Methodology, Literature Review and Future Directions / Keith L Shelton, Robert L Balster -- Drug Discrimination Studies in Rhesus Monkeys: Drug Dependence and Withdrawal / Jun-Xu Li, Lisa R Gerak, Charles P France -- Human Drug Discrimination: Methodological Considerations and Application to Elucidating the Neuropharmacology of Amphetamines / Craig R Rush, Andrea R Vansickel, William W Stoops -- Nicotine Discrimination in Humans / Kenneth A Perkins -- Drug Discrimination: A Perspective / Francis C Colpaert -- Index.

Although somewhat labor intensive, Drug Discrimination (DD) is of enormous applicability to the understanding of drug action. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies covers the practical applications of drug discrimination studies for medicinal chemistry, including strengths and limitations versus other pharmacological methods for evaluating drug action. The book provides medicinal chemists with a fuller understanding of the nature and use of drug discrimination studies for evaluating the action of drugs while helping pharmacologists understand and better interact with medicinal chemists and drug designers when sharing pharmacologic data.

ISBN: 9781118023150 (electronic bk.)

Standard No.: 9786613239716

Source: 10.1002/9781118023150Wiley InterSciencehttp://www3.interscience.wiley.comSubjects--Topical Terms:

322667
Drug discrimination (Pharmacology)
Index Terms--Genre/Form:

228523
Electronic books.

LC Class. No.: RM302.7 / .D784 2011eb

Dewey Class. No.: 615/.19

National Library of Medicine Call No.: QV 4

Drug discriminationapplications to medicinal chemistry and drug studies /
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245 0 0 $a Drug discrimination $h [electronic resource] : $b applications to medicinal chemistry and drug studies / $c edited by Richard A. Glennon, Virginia Commonwealth University, Richard Young, Virginia Commonwealth University.
260 $a Hoboken, N.J. : $c c2011. $b Wiley,
300 $a 1 online resource (xx, 510 p.) : $b ill.
504 $a Includes bibliographical references and index.
505 0 $a Frontmatter -- Color Plates -- Part I. Part Introduction -- An Introduction to Drug Discrimination -- Methodological Considerations -- Drug Discrimination: Practical Considerations -- Role of Stereochemistry in Drug Discrimination Studies -- Drug Discrimination and In Vivo Structure b6 sActivity Relationships -- Drug Discrimination and Mechanisms of Drug Action -- Drug Discrimination and Development of Novel Agents and Pharmacological Tools -- Appendix -- Part II. Part Introduction -- Perceptual Drug Discriminative Aspects of the Endocannabinoid Signaling System in Animals And Man / Torb�jrn U C �Jrbe -- Discriminative Stimulus Properties of Receptor Antagonists / Joseph H Porter -- The Discrimination of Drug Mixtures / Ian P Stolerman -- Making the Right Choice: Lessons From Drug Discrimination for Research on Drug Reinforcement And Drug Self-Administration / S Stevens Negus, Matthew L Banks -- Inhalant Drug Discrimination: Methodology, Literature Review and Future Directions / Keith L Shelton, Robert L Balster -- Drug Discrimination Studies in Rhesus Monkeys: Drug Dependence and Withdrawal / Jun-Xu Li, Lisa R Gerak, Charles P France -- Human Drug Discrimination: Methodological Considerations and Application to Elucidating the Neuropharmacology of Amphetamines / Craig R Rush, Andrea R Vansickel, William W Stoops -- Nicotine Discrimination in Humans / Kenneth A Perkins -- Drug Discrimination: A Perspective / Francis C Colpaert -- Index.
505 0 $a An introduction to drug discrimination -- Methodological considerations -- Drug discrimination : practical considerations? -- Role of stereochemistry in drug discrimination studies -- Drug discrimination and in vivo structure-activity relationships -- Drug discrimination and mechanisms of drug action -- Drug discrimination and development of novel agents and pharmacological tools -- Perceptual drug discriminative aspects of the endocannabinoid signaling system in animals and man -- Discriminative stimulus properties of receptor antagonists -- The discrimination of drug mixtures -- Making the right choice : lessons from drug discrimination for research on drug reinforcement and drug self-administration -- Inhalant drug discrimination: methodology, literature review, and future directions -- Drug discrimination studies in rhesus monkeys : drug dependence and withdrawal -- Human drug discrimination : methodological considerations and application to elucidating the neuropharmacology of amphetamines -- Nicotine discrimination in humans -- Drug discrimination : a perspective.
520 $a Although somewhat labor intensive, Drug Discrimination (DD) is of enormous applicability to the understanding of drug action. Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies covers the practical applications of drug discrimination studies for medicinal chemistry, including strengths and limitations versus other pharmacological methods for evaluating drug action. The book provides medicinal chemists with a fuller understanding of the nature and use of drug discrimination studies for evaluating the action of drugs while helping pharmacologists understand and better interact with medicinal chemists and drug designers when sharing pharmacologic data.
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