| 紀錄類型: |
書目-語言資料,印刷品
: Monograph/item
|
| 正題名/作者: |
Chromatin deregulation in cancer :/ edited by Scott A. Armstrong, Steven Henikoff, Christopher R. Vakoc. |
| 其他題名: |
a subject collection from Cold Spring Harbor perspectives in medicine / |
| 其他作者: |
Vakoc, Christopher R. |
| 出版者: |
Cold Spring Harbor, N.Y. :Cold Spring Harbor Laboratory Press, : c2017., |
| 面頁冊數: |
vii, 382 p. :ill. (some col.) ; : 27 cm.; |
| 提要註: |
"The machinery that controls how DNA is packaged and genes are activated plays an important role in cancer. This book examines the functions of components of this machinery, how they can be dysregulated, and the prospects for targeting them therapeutically. Highlights include: - PRC2 polycomb complex - Therapy- Lysine demethylase inhibitors - Epigenetic mechanisms of therapy resistance and tumor heterogeneity - Long non-coding RNA"-- |
| 標題: |
Neoplasms - genetics. - |
| ISBN: |
9781621821403 (hard) : |