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DNA replication/

American Chemical Society.

DNA replication/

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	DNA replication/ / Anastasia Sosenko Piscitello, Michalis Petropoulos, Sotirios K. Sotiriou & Thanos D. Halazonetis.
作者:	Piscitello, Anastasia Sosenko,
其他作者:	Petropoulos, Michalis,
出版者:	Washington, DC, USA: American Chemical Society, : 2022,
面頁冊數:	1 online resource :illustrations (some color). :
提要註:	"Abnormal DNA replication is the primary way that cancer develops in mammals; therefore, a deep understanding of the way replication works for healthy cells will enhance our ability to eradicate problematic replication pathways. The same rapid advances in technology within the last ten to twenty years that have allowed us to understand DNA replication better have also led and will lead to new cancer therapies. In recent years, our understanding of the complexity of DNA replication has advanced tremendously. This e-book distills the bulk of the published studies in DNA replication with an intentional focus on eukaryotes, specifically, budding yeast and mammals. An important feature of this e-book is the incorporated images and figures. Being able to clearly visualize protein and enzymatic processes is central to understanding them. Therefore, we have incorporated images of the three-dimensional structures of the proteins that mediate DNA replication, stepwise guides to simplify the complex nature of the replication process, and cryo-EM images for different proteins and protein-DNA complexes to reveal their structural components. We hope to have provided readers with both fundamentals and cutting-edge information so that they may think about the biology of DNA replication and contribute to the body of knowledge in the field."--
標題:	DNA replication. -
電子資源:	https://er.kmu.edu.tw/user/login/?next=/er/geter/EB000211607/
ISBN:	9780841299306(ebook):

DNA replication/
Piscitello, Anastasia Sosenko,

DNA replication/ Anastasia Sosenko Piscitello, Michalis Petropoulos, Sotirios K. Sotiriou & Thanos D. Halazonetis. - Washington, DC, USA: American Chemical Society, 2022 - 1 online resource :illustrations (some color). - ACS in focus,2691-8307. - ACS in focus,.

Includes bibliographical references and index.

DNA Structure and DNA Replication Basics --

"Abnormal DNA replication is the primary way that cancer develops in mammals; therefore, a deep understanding of the way replication works for healthy cells will enhance our ability to eradicate problematic replication pathways. The same rapid advances in technology within the last ten to twenty years that have allowed us to understand DNA replication better have also led and will lead to new cancer therapies. In recent years, our understanding of the complexity of DNA replication has advanced tremendously. This e-book distills the bulk of the published studies in DNA replication with an intentional focus on eukaryotes, specifically, budding yeast and mammals. An important feature of this e-book is the incorporated images and figures. Being able to clearly visualize protein and enzymatic processes is central to understanding them. Therefore, we have incorporated images of the three-dimensional structures of the proteins that mediate DNA replication, stepwise guides to simplify the complex nature of the replication process, and cryo-EM images for different proteins and protein-DNA complexes to reveal their structural components. We hope to have provided readers with both fundamentals and cutting-edge information so that they may think about the biology of DNA replication and contribute to the body of knowledge in the field."--

ISBN: 9780841299306(ebook): NT2900Subjects--Topical Terms:

521181
DNA replication.
Index Terms--Genre/Form:

228523
Electronic books.

National Library of Medicine Call No.: QU137 / P676

DNA replication/
LDR:02489nam a2200241 i 4500 001 389462
003 DACS
005 20220412120312.0
008 251103s2022 dcua ob 101 0 eng d
020 $a 9780841299306(ebook): $c NT2900
040 $a KMU
060 0 4 $a QU137 $b P676
100 1 $a Piscitello, Anastasia Sosenko, $e author. $u University of Geneva. $3 521177
245 0 0 $a DNA replication/ $c Anastasia Sosenko Piscitello, Michalis Petropoulos, Sotirios K. Sotiriou & Thanos D. Halazonetis.
260 1 $a Washington, DC, USA: $b American Chemical Society, $c 2022
300 $a 1 online resource : $b illustrations (some color).
336 $a text $2 rdacontent
337 $a computer $2 rdamedia
338 $a online resource $2 rdacarrier
490 1 $a ACS in focus, $x 2691-8307
504 $a Includes bibliographical references and index.
505 0 0 $t DNA Structure and DNA Replication Basics -- $t Classes of Proteins That Function in DNA Replication -- $t Origins of DNA Replication -- $t Initiation of DNA Replication -- $t DNA Replication Elongation -- $t Replication Termination -- $t Concluding Remarks.
520 # $a "Abnormal DNA replication is the primary way that cancer develops in mammals; therefore, a deep understanding of the way replication works for healthy cells will enhance our ability to eradicate problematic replication pathways. The same rapid advances in technology within the last ten to twenty years that have allowed us to understand DNA replication better have also led and will lead to new cancer therapies. In recent years, our understanding of the complexity of DNA replication has advanced tremendously. This e-book distills the bulk of the published studies in DNA replication with an intentional focus on eukaryotes, specifically, budding yeast and mammals. An important feature of this e-book is the incorporated images and figures. Being able to clearly visualize protein and enzymatic processes is central to understanding them. Therefore, we have incorporated images of the three-dimensional structures of the proteins that mediate DNA replication, stepwise guides to simplify the complex nature of the replication process, and cryo-EM images for different proteins and protein-DNA complexes to reveal their structural components. We hope to have provided readers with both fundamentals and cutting-edge information so that they may think about the biology of DNA replication and contribute to the body of knowledge in the field."-- $c Provided by publisher.
590 $a American Chemical Society, ACS In Focus eBooks - 2022 Front Files.
650 # 0 $a DNA replication. $3 521181
650 1 2 $2 96060 $a Eukaryotic Cells. $3 240764
650 1 2 $a DNA Replication $x physiology. $3 521182
655 # 0 $a Electronic books. $2 local $3 228523
700 1 # $a Petropoulos, Michalis, $e author. $u University of Geneva. $3 521178
700 1 # $a Sotiriou, Sotirios K., $e author. $u FoRx Therapeutics. $3 521179
700 1 # $a Halazonetis, Thanos D., $e author. $u University of Geneva. $3 521180
710 2 # $2 97100 $a American Chemical Society. $3 236335
830 0 $a ACS in focus, $x 2691-8307 $3 521128
856 4 # $u https://er.kmu.edu.tw/user/login/?next=/er/geter/EB000211607/